The Nano-Bio Lab focuses on the sensing and detection of medically important biomolecules and diseased cells. We develop novel structures, substrates, microfluidic systems and electronic devices using microtechnology and nanotechnology tools and tricks. Our research spans many domains, all focused towards specific and ultrasensitive nanoscale characterization of biological processes.
Nanotechnology for Cancer Detection | Samir Iqbal | TEDxUTA
Electrical detection of cancer biomarker using aptamers with nanogap break-junctions
Electrical fingerprinting, 3D profiling and detection of tumor cells with solid-state micropores
Nanotechnology for Cancer Detection | Samir Iqbal | TEDxUTA
Selected Publications
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N. Mansur, M. R. Hasan, Z. I . Shah, F. J. Villarreal, Y.-T. Kim, and S. M. Iqbal, "Discrimination of metastatic breast cancer cells from indolent cells on aptamer-functionalized surface with imaging-based contour-following techniques," Biomedical Physics & Engineering Express, vol. 4, no. 2, pp. 025038 (12 pp) (2018). DOI: 10.1088/2057-1976/aa942a
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M. R. Hasan, N. Hassan, R. Khan, Y.-T. Kim, and S. M. Iqbal, "Classification of Cancer Cells using Computational Analysis of Dynamic Morphology,” Computer Methods and Programs in Biomedicine, vol. 156, pp 105-112 (2018). DOI: 10.1016/j.cmpb.2017.12.003
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N. Mansur, M. R. Hasan, Y.-T. Kim and S. M. Iqbal, "Functionalization of Nanotextured Substrates for Enhanced Identification of Metastatic Breast Cancer Cells," Nanotechnology, vol. 28, no. 38, pp. 385101 (11 pp) (2017). DOI: 10.1088/1361-6528/aa7f84
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W. Ali, A. Ilyas, L. Bui, B. Sayles, Y. Hur, Y.-T. Kim and S. M. Iqbal, "Differentiating Metastatic and Non-metastatic Tumor Cells from their Translocation Profile through Solid-state Micropores," Langmuir, vol. 32, no. 19, pp 4924–4934 (2016). DOI: 10.1021/acs.langmuir.6b00016
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M. Islam, M. M. Bellah, A. Sajid, M. R. Hasan, Y.-t. Kim and S. M. Iqbal, "Effects of Nanotexture on Electrical Profiling of Single Tumor Cell and Detection of Cancer from Blood in Microfluidic Channels," Scientific Reports, vol. 5, no. 13031, pp. 1-9 (2015). DOI: 10.1038/srep13031
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M. A. I. Mahmood, M. R. Hasan, U. J. M. Khan, P. B. Allen, Y.-t. Kim, A. D. Ellington and S. M. Iqbal, "One-step tumor detection from dynamic morphology tracking on aptamer-grafted surfaces," Technology, vol. 3, no. 4, pp. 1-7 (2015). DOI: 10.1142/S2339547815500089
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H. Ma, J. Liu, M. M. Ali, M. A. I. Mahmood, L. Labanieh, M. Lu, S. M. Iqbal, Q. Zhang, W. Zhao, and Y. Wan, "Nucleic Acid Aptamers in Cancer Research, Diagnosis and Therapy," Chemical Society Reviews, vol. 44, pp. 1240-1256 (2015). DOI: 10.1039/C4CS00357H
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A. Ilyas, W. Asghar, S. Ahmed, Y. Lotan, J.-T. Hsieh, Y.-t. Kim and S. M. Iqbal, "Electrophysiological Analysis of Biopsy Samples using Elasticity as an Inherent Cell Marker for Cancer Detection," Analytical Methods, vol. 6, no. 18, pp. 7166-7174 (2014). DOI: 10.1039/C4AY00781F (Cover Article)
News
Jan 11, 2018
Dr. Iqbal gave a talk to Research and Innovation Division of Mara University of Technology, Shah Alam, Malaysia
Dec 14, 2017
Dr. Iqbal elected as IEEE-Nanotechnology Council Distinguished Lecturer for 2018
Nov 13, 2017
Congrats to Dr. M. Raziul Hasan on successful Dissertation Defense.
Aug 22, 2017
Congrats to Dr. Nuzhat Mansur on defending her PhD with flying colors.
Sep 05, 2017
Dr. Iqbal taught a tutorial “Nanotextured Systems for Biomedical Sensing” at the NANOSMAT School in Pierre Marie Curie University, Paris, France
Apr 04, 2017
Dr. Iqbal speaks at TEDxUTA about Nanotechnology for Cancer Detection
May 05, 2016
Congratulations to Usman Raza for winning the 2016 Outstanding GTA Award.